MR imaging in pseudoxanthoma elasticum.

Gri:inblad-Strandberg syndrome known as pseudoxanthoma elasticum (PXE) is a rare connective tissue disorder, the inheritance of which shows both autosomal and recessive characteristics [1]. The disease most commonly involves the skin , eyes , cardiovascular system, and gastrointestinal tract [2]. The vascular connective tissue supporting the retina, known as the Bruch membrane, tends to calcify [3] . Arterial calcifications may result in a variety of clinical manifestations including hypertension; angina; and neurologic deficits caused by ischemia , infarction, or hemorrhage [4 , 5].